CovariatesCovariates comprised sex, age, education, alcohol consumption, body mass index (BMI), physical activity, history of diabetes, total cholesterol, and systolic blood pressure. All of these variables were measured at baseline. Education was categorised into low, moderate, and high, which was either based on the highest level of education (low: primary education or less; moderate: more than primary but less than college or university education; high: college or university education), or on the number of years in full time education which was then translated into categories (low: 19 For SHARE three categories were defined on the basis of the usual drinking pattern according to the number of days per week on which alcohol was drunk (non drinker: self reported non drinking; moderate drinker: drinking on =2 days per week; heavy drinker: drinking on =3 days per week).

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